Patients With EGFR-Mutant NSCLC May Benefit from Targeted Therapy More Than...
Immunotherapy has changed the way lung cancer is treated in many patients. But as the use of these drugs expands—including to patients with earlier stages of the disease—it’s become increasingly...
View ArticleMeet Anthony D’Amico, MD, PhD
Anthony D’Amico, MD, PhD, Chief of Genitourinary Radiation Oncology at Dana-Farber Brigham Cancer Center, and Eleanor Theresa Walters Distinguished Chair in Radiation Oncology, is renowned for his...
View ArticleEffects of Modafinil on Cognition and Sleep Quality in Affectively Stable...
Most patients with bipolar disorder experience circadian dysfunction and deficits in attention, verbal memory, and executive functioning, even during periods of euthymia. Katherine E. Burdick, PhD,...
View ArticleThree Studies Find Statins Protect Against Cardiovascular Disease in...
The 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults reported no evidence for using statins in people over 75 years of age. That...
View ArticleStudy Focuses on Molecular Changes Associated With Different Kinds of...
Endometriosis affects up to 10% of women of reproductive age, yet the underlying molecular drivers of the disease are not well understood. The primary symptom of the disease is pelvic pain, which can...
View ArticleNew Center Aims to Close Gap in Care for Postpartum Women
Maternal morbidity and mortality rates are considerably higher in the United States than in most peer nations. A troubling gap in the care of postpartum women is likely an important contributor to the...
View ArticleImproving Outcomes in Skull Base Surgery: Avoiding Inner Ear Breaches During...
Recent attention has been drawn to symptomatic effects of injuries to the delicate structures of the temporal bone including the cochlea (hearing organ), vestibule, and the balance canals (balance...
View ArticleBrigham and Women’s Becomes First Hospital in New England to Achieve ACS...
The number of aging Americans and their need for comprehensive healthcare is only growing. About 40% of surgical patients at Brigham and Women’s Hospital are over the age of 65, and on average, these...
View ArticleNew Research Uncovers Biological Drivers of Heart Disease Risk
Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk and coronary artery disease (CAD). In an effort to streamline the analysis...
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Researchers Discover Role of PD-1 in Driving Growth of Merkel Cell Carcinoma
Programmed cell death 1 (PD-1) is a critical protein in T cells, making it an important target for immune checkpoint inhibitor drugs. In recent years, research has revealed that some cancer cells also...
View ArticleAdvancing the Understanding of Bariatric Surgery Outcomes
Members of the Division of General and Gastrointestinal Surgery in the Department of Surgery at Brigham and Women’s Hospital were authors of three recently published retrospective studies focused on...
View ArticleReview: Mental Health Over the Menopause Transition
A 1959 paper in the Journal of the American Medical Association described menopause as a “rather unpleasant and possibly dangerous” period of life and presented what became the first widely used...
View ArticlePatterns and Disparities in Telehealth Usage Across Surgical Specialties...
The COVID-19 pandemic has accelerated use of telehealth, but there’s been concern about whether surgical specialties can deliver adequate care in this manner. Quoc-Dien Trinh, MD, MBA, director of...
View ArticleHigh Investigational Doses of Oral Semaglutide Safe and Efficacious for...
Based on data from the PIONEER clinical trial program, semaglutide is approved at once-daily oral doses of 7 mg or 14 mg for the treatment of type 2 diabetes (T2D) in adults. Data from the latest study...
View ArticlePushing the Boundaries of Research and Clinical Care in Pancreatic Cancer
From novel laboratory research that enables scientists to define pancreatic cancer cells better to innovative clinical approaches that help patients recover from surgery more quickly, Dana-Farber...
View ArticleBariatric Surgery Provides Long-Term Blood Glucose Control in Patients With...
A growing body of evidence indicates bariatric surgery is superior to medical and lifestyle therapies for the treatment of type 2 diabetes (T2D). Yet, randomized clinical trials of bariatric surgery...
View ArticleHeart Rhythm 2024: Brigham Presents Electrophysiology Research
Members of the Heart and Vascular Center at Brigham and Women’s Hospital will join the global electrophysiology community at Heart Rhythm 2024. This annual meeting and educational program, hosted by...
View ArticleImmunoprofiling Can Identify Immune Cell Abnormalities, Guide Care for...
Researchers at Brigham and Women’s Hospital have demonstrated that for patients with unusual autoimmune or inflammatory conditions, cellular and transcriptomic immunophenotyping can serve as...
View ArticleCertain Plasma Metabolites and Metabolite Classes Linked to Persistent Tinnitus
Metabolites are downstream of the genetic transcription process, reflecting direct input from the diet, environment, and intestinal microbiome. Systematic analyses of metabolites have identified...
View ArticleNoninvasive Prenatal Test Detects Fetal Antigens
Hemolytic disease of the fetus and newborn (HDFN) most commonly occurs when an RhD-negative pregnant person is exposed to antigens from an RhD-positive fetus. For RhD-negative pregnant patients in the...
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